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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ROS1
All Species:
18.18
Human Site:
Y2115
Identified Species:
40
UniProt:
P08922
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08922
NP_002935.2
2347
263915
Y2115
D
I
Y
K
N
D
Y
Y
R
K
R
G
E
G
L
Chimpanzee
Pan troglodytes
XP_527487
2347
263893
Y2115
D
I
Y
K
N
D
Y
Y
R
K
R
G
E
G
L
Rhesus Macaque
Macaca mulatta
XP_001110859
2345
263559
Y2113
D
I
Y
K
N
D
Y
Y
R
K
R
G
E
G
L
Dog
Lupus familis
XP_541215
2048
229894
A1835
G
T
G
E
T
K
V
A
V
K
T
L
K
K
G
Cat
Felis silvestris
Mouse
Mus musculus
Q78DX7
2340
261949
Y2108
E
I
Y
K
N
D
Y
Y
R
K
R
G
E
G
L
Rat
Rattus norvegicus
Q63132
2338
261637
Y2107
E
I
Y
K
H
D
Y
Y
R
K
R
G
E
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518175
2242
244778
L2029
A
V
V
I
G
D
D
L
G
P
A
G
P
A
L
Chicken
Gallus gallus
P08941
2311
260942
L2096
M
R
F
I
H
R
D
L
A
A
R
N
C
L
V
Frog
Xenopus laevis
O73798
1358
153845
V1145
M
V
T
E
D
F
T
V
K
I
G
D
F
G
M
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P13368
2554
287007
V2327
L
L
A
M
C
I
D
V
A
N
G
C
S
Y
L
Honey Bee
Apis mellifera
XP_394148
2105
237988
G1892
V
L
E
L
M
E
A
G
D
L
L
S
Y
L
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.1
96.6
73.4
N.A.
79.8
79.8
N.A.
33.7
53.2
21
N.A.
N.A.
23.1
26.8
N.A.
N.A.
Protein Similarity:
100
99.5
98.2
79.8
N.A.
88.3
87.9
N.A.
47.7
68.7
34.9
N.A.
N.A.
40
45.5
N.A.
N.A.
P-Site Identity:
100
100
100
6.6
N.A.
93.3
86.6
N.A.
20
6.6
6.6
N.A.
N.A.
6.6
0
N.A.
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
26.6
26.6
40
N.A.
N.A.
13.3
13.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
10
0
0
0
10
10
19
10
10
0
0
10
0
% A
% Cys:
0
0
0
0
10
0
0
0
0
0
0
10
10
0
0
% C
% Asp:
28
0
0
0
10
55
28
0
10
0
0
10
0
0
0
% D
% Glu:
19
0
10
19
0
10
0
0
0
0
0
0
46
0
0
% E
% Phe:
0
0
10
0
0
10
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
10
0
10
0
0
10
10
0
19
55
0
55
10
% G
% His:
0
0
0
0
19
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
46
0
19
0
10
0
0
0
10
0
0
0
0
0
% I
% Lys:
0
0
0
46
0
10
0
0
10
55
0
0
10
10
0
% K
% Leu:
10
19
0
10
0
0
0
19
0
10
10
10
0
19
64
% L
% Met:
19
0
0
10
10
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
37
0
0
0
0
10
0
10
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
10
0
0
10
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
10
0
0
0
10
0
0
46
0
55
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
0
0
0
0
10
10
0
0
% S
% Thr:
0
10
10
0
10
0
10
0
0
0
10
0
0
0
0
% T
% Val:
10
19
10
0
0
0
10
19
10
0
0
0
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
46
0
0
0
46
46
0
0
0
0
10
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _